Cesium and Cancer
Germanium
-
The health and life enhancer
by Sandra Goodman, Ph.D.
Chapter 7:
Germanium's Action Against Cancer
Cancer - A Philosophical Treatise
We must go back to basics to answer the question "what
is cancer?". We are so conditioned to going into a
state of shock at the very mention of the word that we hardly
think rationally of just what cancer is. It is, stated very
simply, the uncontrolled proliferation of cells. Normally,
our immune system can handle foreign cells, toxins, and
abnormal, cancerous cells. However, due to a multiplicity
of factors, perhaps genetic predisposition, poor diet, toxic
environmental attack, recreational abuse, negativity and
depression, our "resistance" weakens, abnormal
cells multiply and start to spread, somehow oblivious to
normal control mechanisms.
Nowhere is the split between allopathic and holistic medicine
more pronounced than in diseases such as cancer. Western
science, stuck in the notion "one disease, one cause",
spends billions of dollars in many highly focused races
to find a cure for a "dis-ease" of a body. Hence
the "search and destroy" methodology of chemotherapy,
radiation therapy, radical surgery, all in the sincere desire
that to be healed, the cancer must be destroyed.
A holistic approach to healing considers all factors of
the individual: psychological/spiritual, emotional, environmental
as well as physical. Where is the cancer? What in that person's
life has caused him to create a cancer in that part of the
body? What is the physical and genetic disposition of the
person, his parents? What has been his diet? How stressful
is his work? Is he fulfilled emotionally and spiritually?
Does he exercise?
Diagnosis and treatment of cancer would ideally utilize,
in a cooperative fashion, the most appropriate techniques
of modern medicine and/or complementary therapies, with
the patient playing an active role in his treatment and
healing (9). This type of treatment would use to maximum
advantage technological advances of modern medicine as well
as the accumulated wisdom of traditional healing practices.
The approaches used with Germanium in the East and West
exemplify almost perfectly the dichotomy between the two
healing traditions. On the one hand, the Asai Germanium
clinic prescribes organic Germanium, along with a non-acid
forming diet and stress counselling for its cancer patients.
On the other extreme, North American oncology groups administer
Spirogermanium in intravenous drips to cancer patients (117),
who have already undergone every other option before being
admitted to the Germanium clinical trial.
Chapter 13 compares and evaluates in detail, the philosophy
and practice of each of these approaches, as well as those
more in the middle. This chapter summarizes the scientific
research which documents organic Germanium as a therapeutic
agent in cancer treatment.
Germanium - Advantages Of Being A Food And A Drug
There are normally several distinct stages whereby a potential
cancer drug is tested before it can be made available. If
the substance demonstrates anticancer activity in a number
of in vitro (in the test tube) assays, then studies on animals
will be conducted. If these studies demonstrate promising
results, then experiments and trials will be conducted with
actual human cancer patients. Because organic Germanium
is a natural substance with virtually no demonstrated toxicity
(see chapter on Safety), Germanium is classified as a food
supplement and not a drug, which has enabled faster progress
in establishing its therapeutic action in humans for many
serious illnessess, including cancer. Thus, treatment of
human cancer patients over almost two decades has occurred
in parallel with the careful scientific studies in animals,
establishing its anticancer action, resulting in a wealth
of documentation from the human side, as well as laboratory
data. There are business and philosophical issues deriving
from this question of "food or drug", which will
be addressed in Chapter 12.
Putting together the cancer research studies of the three
organic Germanium compounds, Ge-132, Sanumgerman and Spirogermanium,
at the cellular level, in animals and human cancer patients,
the evidence for organic Germanium's anticancer properties
is solid and reproducible. This chapter will highlight the
research results in these various areas.
Cellular Level
1. The Allium test uses actively dividing plant cells to
measure the anticancer or oncostatic activity of a potential
anticancer substance. Sanumgerman, when analyzed by this
procedure, showed the characteristics of an active compound
(36,54,62).
2. Tests with various laboratory cancerous cell lines demonstrated
that Spirogermanium significantly inhibited DNA, RNA and
protein synthesis of these cancer cells at very low concentrations
(88,118).
3. Further characterization of organic Germanium's mode
of action at the cellular and molecular level, showed that
Germanium compounds inhibited viral (HSV-1) replication
in vitro and blocked the synthesis of DNA in hepatoma 22A
and ovarian cancer cells (39,40,68).
Animal Studies
1. Sanumgerman's antitumour activity with several types
of cancers has been documented in mice. In one study, the
group of mice which received Sanumgerman had a 20% incidence
of tumours, compared to 50% in the control group (13). Also,
Sanumgerman administered to mice with carcinoma of the colon
survived longer (61). In other studies, Sanumgerman showed
positive results against colon, lung and Myeloma type cancers
(60).
2. In studies with rats, Spirogermanium was shown to increase
the lifespan by 500% of animals with Walker type carcinoma
(115).
3. Ge-132 has shown significant antitumour activity against
a wide spectrum of tumours (53,58,71,101), which has been
elegantly shown to be mediated by activation of immune mechanisms,
including macrophages, natural killer cells, interferon
and T-suppressor cells (see also chapter 3).
The above-cited animal studies with organic Germanium compounds
were conducted by a variety of established scientific groups
around the world, in accordance with scientifically accepted
protocols, such as those set down by the National Cancer
Institute, USA. The results have been published in learned
refereed scientific journals, attesting to the fact that
the methodology and data analysis were subjected to controls
associated with scientific metholody. Although this in itself
is no guarantee of a substance's efficacy in humans, it
does attest to the fact that organic Germanium compounds
demonstrate significant anticancer activity in laboratory
animals infected with a wide range of different cancers.
Human Cancer Patients
Clinical Trials
1. Clinical trials on lung cancer showed a statistically
significant effect of Ge-132 upon life prolongation, tumour
regression and overall improvement in performance status
and immunological parameters. A double-blind controlled
study for unresectable lung cancer was commenced in 1980
(71). The patients were divided into classes, depending
on the type of cancer. The treatments consisted either of
chemotherapy plus Ge-132, or chemotherapy plus a placebo,
administered double-blind, meaning that neither the patient
nor the doctor knew whether the individual was receiving
Germanium or the placebo. Interim results to date revealed
a significant difference between the placebo and Ge-132
in the proportion of partial and complete responses to treatment
with organic Germanium.
2. A technical document issued by the Asai Germanium Research
Institute, compiles clinical and research data on the pharmacological,
immunological and toxicological properties of Ge-132 (30).
The long list of studies, trials and investigators in the
Appendix attests to the intense research activity ongoing
in Japan, to "evaluate strictly the therapeutic efficacy
of Ge-132".
3. A clinical study of Sanumgerman's effectiveness against
ovarian malignancy was conducted with 6 women, aged 44-64,
who had been operated for malignant tumours of the ovaries
and uterus (85). The well-being of all these patients improved
considerably, and they experienced considerable relief from
pain. The remarkable analgesic (pain-relieving) properties
of organic Germanium are reviewed in chapter . In five out
of the six women, there was no exudate formation in the
abdominal or inner pelvic cavity; a slight exudate was observed
in the sixth woman.
4. A Phase I clinical trial was conducted with 35 patients
with a variety of cancers, with intravenously administered
Spirogermanium (88,89). This trial was conducted in order
to define a tolerated dosage and to determine anticancer
activity. Several of the patients experienced mild and transient
side effects such as dizziness which were all resolved within
a few minutes to several hours. There was no evidence of
cumulative toxicity, nor of bone marrow depression. One
patient showed a partial response in the palpable lymph
nodes for 2 months.
5. A Phase II trial for patients with lymphoma-proliferative
disease (non-Hodgkin's lymphoma and Hodgkin's disease) was
conducted with Spirogermanium. Out of 17 patients, 5 (30%)
demonstrated an objective response, including 2 complete
responses. No hematological toxicity was observed (88).
Excerpted Case Histories
1. Reduction in the size of a splenic tumour was achieved
after 3 week's Sanumgerman, orally administered to a 62
year old woman with myeloproliferate syndrome (55).
2. An 18-year old male with embryonal cancer of the testicles
and lung filae, undergoing a variety of therapeutic regimes,
including Sanumgerman, recovered, with no metastases up
to the present (1985) (85).
3. A 55 year old woman who had been operated on for Sigmcarcinoma,
developed metastases in the stomach, kidney, mesenterium
and liver. Following cytostatic (chemo) therapy, she received
Sanumgerman treatment. Dark-field analysis of her red blood
picture was closely monitored. After 3 months of treatment
with Sanumgerman, there was a significant decrease in erythrombic
development, with considerable improvement in cell respiration.
Four years after the operation, there was NO trace of liver
metastases, although the size of the tumour and lymphatic
ganglion slightly increased (77).
4. A 78 year old male with colon cancer and liver metastases
was operated on in 1978 and again in 1979. Liver metastases
were discovered in 1982, upon which biological therapy,
a strict cancer diet and Sanumgerman therapy was initiated.
After 1 year, there were no metastases in a clinical examination,
which was the same situation a further 3 years later (120).
5. A 54 year old man with a large bean-size cancerous growth
on the right lung, after taking anticancer drugs lost his
appetite and was losing his strength. Five weeks after taking
500 mg daily Ge-132, X-rays showed absolutely no trace of
cancer, the dry cough had disappeared and his overall condition
improved to his former state of good health (2).
These few case histories represented a small fraction of
the "anecdotal" evidence that has accumulated,
attesting to organic Germanium's therapeutic effectiveness
in treating cancer. Not all cancer patients receiving organic
Germanium have been cured; minimal therapeutic effect has
been noted in several clinical trials with intravenously
administered Spirogermanium. As is discussed in in Chapter
13, this may in part reflect the trial selection and administration
procedures.
However almost invariably a general overall improvement
in the quality of life occurs, due in large part to organic
Germanium's ability to relieve pain. Anecdotal case histories
are not considered by scientists to be proof of a substance's
efficacy, because it cannot be rigorously proved that the
patient was cured by the particular substance in question.
Greater agreement about methodology in clinical testing
must occur if an integration between western science and
holistic medicine can occur. Holistic medicine takes as
a given that the true healer is the individual himself,
who, in taking whatever treatment he does, is enabling his
body's own healing powers to restore him to health. Combining
scientific rigour with holistic compassion will increase
an individual's course of therapeutic progress.
Angstrom Minerals Product And Price List
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Nutrition/Germanium/chapter7.htm.